Consultations offered at our five convenient locations in Calhoun, GA, Chattanooga, TN, Ooltewah, TN, Franklin, TN and Blueridge, GA

Exosomes are microscopic particles produced and released by many different types of cells. They hold fats, proteins, substances called nucleic acids, and many more molecules helpful in cellular repair and regeneration. By applying exosomes topically as a formulation called exosome regenerative complex after procedures such as Sylfirm X, you can achieve noticeably younger-looking, revitalized skin. 

Scientists have begun to unlock the full therapeutic potential of exosomes, which are revolutionizing the field of regenerative medicine. For more information on exosomes, the physicians at Southern Surgical Arts will be able to guide you. To get started today, call (800) 950-0492 or complete our contact form online to book your consultation. We have locations in several areas of the South, including:

Before and After Photos

Exosomes: Uncovering the Power of Cellular Communication

Regenerative medicine is a branch of science that studies various therapies and treatments for the purpose of getting the body to repair and heal itself. As an example of regenerative therapy, topical exosomes work in harmony with your skin- leading to the naturally attained aesthetic results you would get from other anti-aging solutions. 

Exosomes make up groups of particles called extracellular vesicles (EVs). They serve to transport materials and facilitate communication between cells. They are an integral part of maintaining functions throughout various types of tissues, and the skin is no exception. As important messenger particles, they serve to: 

  • Help in the process of wound healing 
  • Remodel the extracellular matrix  – the skin’s structural scaffold
  • Facilitate functions of the immune system 
  • Help with the formation of new blood vessels (angiogenesis)
  • Maintain the health of cell growth and proliferation. (2)

Benefits of Topical Exosome Therapy 

Exosomes offer numerous benefits, making them an attractive option for those seeking natural and non-invasive treatments: 

  • Can be paired with another medspa treatment such as microneedling or laser skin resurfacing. 
  • Utilizes a topical formulation- no injections are required! 
  • Exosomes easily travel from cell to cell due to their small size, making them capable of reaching treatment sites much faster. 
  • They are produced naturally in the body, so there is no risk of toxicity. 
  • Exosomes derived from stem cells have been studied as a “promising alternative” to stem cell therapy– a treatment in which the body’s healing processes are provoked within the cartilage, tendons, ligaments, and muscles for recovery from injuries. (3)

Patients can expect to see an improvement in various aspects of the skin, including: 

  • Improved complexion and tone evenness 
  • Reduced fine lines and wrinkles 
  • Improved skin moisture and elasticity 
  • Reduction of atrophic scars 
  • Nourished skin of the scalp, promoting healthy hair growth
  • Reduced of age spots, rosacea, and other pigmentation issues 

What Do Exosomes Carry? 

As transporters of valuable materials, exosomes are able to carry a number of molecules and nutrients essential for skin health, such as: 

  • Growth Factors – Growth factors are molecules that signal cell growth and division. There are numerous types of growth factors, but there are several designated for skin health carried by exosomes. 
  • Peptides – These are smaller chains of amino acids, a type of organic compound, that function as building blocks to connective proteins like collagen and elastin. 
  • RNA – A type of “translator” and deliverer of genetic instructions to structures called ribosomes within skin cells. These ribosomes are then able to produce the necessary proteins to keep the cell healthy and functional. 
  • Lipids – These are fats that provide the skin protection from environmental hazards and bacteria. They also work to help with moisture retention, allowing the skin to maintain a healthy, radiant glow. 
  • Nucleic Acids – Compounds that are responsible for storing genetic information and the creation of new proteins in the body; they are like blueprints for DNA and RNA. (1) 

Skin Cells & Exosomes

When applied topically to the skin, the exosomes directly interact with fibroblasts, keratinocytes, and immune cells. Maintenance of fibroblast cells is critical for the health of the dermis since they make up such a large portion of it. These cells work to produce collagen, elastin, and other proteins that keep the skin supple and youthful

Exosomes also aid keratinocytes, another type of skin cells that offer protection against UV radiation and harmful microbes. Finally, exosomes are capable of regulating immune functions- ensuring that there is not too little or too much inflammation. This regulation also includes the maintenance, growth, and proliferation of immune cells themselves.

Personal Consultation

When it comes to the fascinating world of exosomes, a personal consultation with one of our skilled team members at Southern Surgical Arts is the ideal starting point for patients to learn more. Our practice, equipped with state-of-the-art technology and a dedicated staff, is committed to providing comprehensive care and innovative treatment options, including the latest in regenerative medicine. 

Contact us today at (800) 950-0492 or send us a request for a consultation through our online form, and we will get back to you as soon as we can. 

Corresponding and Complementary Treatments 

Sylfirm X 

Sylfirm X is a type of advanced microneedling treatment that allows exosomes to penetrate the skin more efficiently and accentuate the skin rejuvenation effects. In summary, microneedling devices cause tiny controlled injuries to the skin that stimulate fibroblast cells to create more connective proteins. Sylfirm X employs radiofrequency (RF) energy that contracts existing collagen to create a skin-tightening effect. The RF is also able to clot the pinpoint amount of blood from the microinjuries, leading to faster recovery. In addition to treating mildly lax skin, it can reduce the size of large pores, minimize scars, and fade stretch marks. 


Morpheus8 is similar to Sylfirm X since it’s a microneedling device that incorporates RF. In Morpheus8, the RF is distributed only in the tips of the needles, rather than the whole needle. This device also operates on a lower amount of power than Sylfirm X; it has 1 MHz v.s. Sylfirm’s 2 MHz. Morpheus8 also has slightly thicker needles, so the microinjuries are slightly more significant. 

Laser Skin Resurfacing 

Southern Surgical Arts offers multiple types of laser treatments including the CO2 laser, ProFractional laser, Halo laser, PicoSure laser, NanoLaserPeel, and MicroLaserPeel. Each laser emits light at a specific wavelength, a term used to describe the frequency of each individual unit of light.  All of our lasers-with the exception of the Halo laser- are purely ablative, meaning that they vaporize the first layer of skin, the epidermis. This means they provide more significant improvement within one treatment session. 

Laser treatments, in general, serve to boost collagen and elastin production which helps eliminate fine lines and wrinkles, improves skin texture and tone, reduces hyperpigmentation and the appearance of age spots, and provides mild skin-firming benefits.

The Halo laser uses fractional light, a technology in which only certain areas of the skin are exposed to thermal energy. With this strategic targeting method, the Halo laser allows for healthy, untouched skin to help with healing the injured areas. The Halo can also be alternated to a nonablative setting in which the epidermis is preserved, but the dermis is affected and stimulated to produce more protein.

The NanoLaserPeel and MicroLaserPeel, also ablative laser treatments, give the doctor or laser technician more settings for customization. For example, the MicroLaserPeel reaches various depths within the dermis of the skin, while the NanoLaserPeel tends to work more superficially. 

Light Therapy 

Intense pulsed light (IPL) is similar to laser skin resurfacing except that it utilizes a wider range of light, utilizing the power of many wavelengths at once. As a nonablative technique, it may require more sessions, but it allows patients to heal much quicker. It is an FDA-approved device for treating broken capillaries under the skin, also called spider veins. This type of redness is often caused by aging, genetics, or sun damage.

Cost of Exosome Therapy in Chattanooga, TN 

Our goal is to provide you with a comprehensive and detailed understanding of the costs involved in your exosome therapy, ensuring transparency and peace of mind throughout your journey towards rejuvenation and well-being. Your doctor will provide you with the estimated cost of your treatment at your personal consultation. To help make the therapy more affordable, Southern Surgical Arts offers two financing options for you to consider: Alphaeon Credit and CareCredit. 

Find out more about the power of exosomes by calling (800) 950-0492 or by sending us a message online.


Can exosome therapy be used cosmetically?

Yes! Exosome therapy has gained significant popularity in cosmetic applications due to its remarkable effectiveness in skin rejuvenation and anti-aging treatment. Whether you’re looking to reduce wrinkles, improve skin texture, stimulate collagen production, or address sun damage, exosome therapy can be a game-changer. It offers a non-surgical and natural approach to cosmetic dermatology, providing patients with long-lasting and natural-looking results.

Does exosome therapy promote collagen production?

Absolutely! One of the key benefits of exosome therapy is its ability to promote collagen production. Collagen is a crucial protein that provides structural support to the skin, giving it strength and elasticity. As we age, collagen production naturally declines, leading to sagging skin and the formation of wrinkles. Exosome therapy stimulates the production of new collagen, helping to restore firmness and youthfulness to the skin. This results in improved skin texture, reduced wrinkles, and a more vibrant complexion.


  1. Blanco, Antonio, and Gustavo Blanco. “Chapter 6 – Nucleic Acids.” ScienceDirect, Academic Press, 1 Jan. 2017, www.sciencedirect.com/science/article/abs/pii/B9780128035504000069
  2. Dinescu S, Dobranici A, Tecucianu R, et al. Exosomes as Part of the Human Adipose-Derived Stem Cells Secretome- Opening New Perspectives for Cell-Free Regenerative Applications. Advances in Experimental Medicine and Biology. Published online 2020:139-163. https://www.doi.org/10.1007/5584_2020_588 
  3. Cho, Byong Seung, et al. “Exosomes Derived from Human Adipose Tissue-Derived Mesenchymal Stem Cells Alleviate Atopic Dermatitis.” Stem Cell Research & Therapy, vol. 9, no. 1, 11 July 2018, https://doi.org/10.1186/s13287-018-0939-5